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This article aims to show the influence of doctrines in the medical lexicographers choices, with the Capuron-Nysten-Littré lineage as a case study. Indeed, the Dictionnaire de médecine has been crossed by several schools of thought such as spiritualism and positivism. While lexical continuity may seem self-evident due to the nature of the work, thus reducing the reprint to a simple lexical increase, this process introduces neologisms and deletions, all can be considered in their effects by using text statistics and factorial analysis.